The big question is: Do they add to your life or subtract from it?
If it is the latter, have you discussed this with them and given them a chance to remedy this together with you?
If they do not care then it is a sign of someone who is not in this relationship for both of you, which is the key component to any relationship.
If they do not want to try, turn it on you, or simply avoid the question this is true too.
At that point it is wishful thinking or nostalgia of how things used to be that keeps you together.
NOTE: This goes both ways. Meaning you may also bring them down and have to open yourself up to help them. But, if this is not a two-way street then it is better to count your losses and move on.
That all being said, this becomes a lot easier to figure out once you make yourself a priority.
Not in terms of pushing the other person out of the way so you are happier, but rather by taking responsibility for your own life and doing what makes you happy.
Make yourself happy first, then make them happy. Both need to be included but in that order.
Once you do you will realize that all a relationship should be is a bonus and something to make you happier not happy overall. With that it becomes easier to identify toxic relationships and non-toxic ones.